A Study of the Mechanism of Cerebral Hyperexcitability after Irradiation
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 46 (4) , 421-424
- https://doi.org/10.1080/09553008414551611
Abstract
Whole-body irradiation at a lethal dose induced an early and transient perturbation of 3H-Muscimol specific binding in the mouse cerebellum. The density of high affinity binding sites was decreased and was associated with a increased affinity. This effect can explain early radio-induced cerebral hyperexcitability. Previous injection of cysteamine, which protects against cerebral hyperexcitability, also offers a good protection against this effect.This publication has 14 references indexed in Scilit:
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