Diagnosis and Treatment of Severe Pediatric Pulmonary Hypertension
- 1 July 2001
- journal article
- review article
- Published by Wolters Kluwer Health in Cardiology in Review
- Vol. 9 (4) , 227-237
- https://doi.org/10.1097/00045415-200107000-00009
Abstract
Advances in the treatment of pulmonary hypertension during the past decade have dramatically improved patient survival. Many of these advances are based on improved understanding of the vascular biology of the normal and hypertensive pulmonary circulations. Pulmonary hypertension is an important determinant of morbidity and mortality in patients with many pediatric diseases, including congenital heart disease. This article describes current diagnostic strategies and treatments for patients with primary and secondary pulmonary hypertension.Keywords
This publication has 61 references indexed in Scilit:
- Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertensionNature Genetics, 2000
- Familial Primary Pulmonary Hypertension (Gene PPH1) Is Caused by Mutations in the Bone Morphogenetic Protein Receptor–II GeneAmerican Journal of Human Genetics, 2000
- RECENT ADVANCES IN THE TREATMENT OF PEDIATRIC PULMONARY ARTERY HYPERTENSIONPediatric Clinics of North America, 1999
- Vasodilator Therapy for Primary Pulmonary Hypertension in ChildrenCirculation, 1999
- Primary Pulmonary HypertensionNew England Journal of Medicine, 1997
- Genetic anticipation and abnormal gender ratio at birth in familial primary pulmonary hypertension.American Journal of Respiratory and Critical Care Medicine, 1995
- Primary pulmonary hypertension in children: Clinical characterization and survivalJournal of the American College of Cardiology, 1995
- Early effects of tissue-type plasminogen activator added to conventional therapy on the culprit coronary lesion in patients presenting with ischemic cardiac pain at rest. Results of the Thrombolysis in Myocardial Ischemia (TIMI IIIA) Trial.Circulation, 1993
- Surgical treatment of adult atrial septal defect: Early and long-term resultsJournal of the American College of Cardiology, 1992
- Pulmonary vascular disease in complete transposition of the great arteries: A study of 200 patientsThe American Journal of Cardiology, 1974