Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21.
- 1 April 1993
- journal article
- Vol. 52 (4) , 767-76
Abstract
In a study of 31 breast cancer families and 12 breast-ovarian cancer families, we have obtained clear evidence of linkage to markers on chromosome 17q in the families with ovarian cancer (maximum lod score 3.34 at theta = .04) but only weak evidence in those without ovarian cancer. Recombinant events indicate that the gene lies between D17S588 and D17S250.This publication has 6 references indexed in Scilit:
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