SUPRARENAL VIRILISM IN A WOMAN

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Abstract
Virchow's statement "propter ovarium solum mulier est quod est" (woman is what she is solely because of the ovary) is refuted by present-day knowledge of the functional relationship of the various ductless glands to the sexual life of woman. Since Apert in 1910 called attention to the influence of a hyperplasia of the suprarenals on the female sex characteristics, numerous contributions to this question have appeared in the literature and abundant clinical material demonstrating this fact has been placed on record. Anatomic studies have appeared explaining this functional relationship: since the anlage of the suprarenal cortex appears to be close to the sex gland anlage, both primordia partly coalesce and hence their functional interdependence in later life. For this clinical relationship Gallais coined the descriptive term "syndrome génitosurrénale." The literature abounds with reports of cases demonstrating this syndrome, in which tumors of the suprarenals cause sex abnormalities. However, it has

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