Evidence that changes in LH pulse frequency may regulate the seasonal modulation of LH secretion in ovariectomized mares

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Abstract
To determine whether tonic LH [luteinizing hormone] secretion in ovariectomized mares is characterized by pulsatile release, frequent blood smaples (every 15 min) were collected from 5 ovariectomized horse mares in nine 8-h periods between Feb. and May. Mean serum LH concentrations increased 9-fold and were associated with a 4-fold increase in mean LH pulse frequency. Pulsatile LH release in ovariectomized mares was evidenced, the increasing daylengths of the spring months may increase serum LH by increasing LH pulse frequency.