Regional assignment of the loci for adenylate kinase to 9q32 and for ?1-acid glycoprotein to 9q31-q32
- 1 April 1989
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 82 (1) , 17-19
- https://doi.org/10.1007/bf00288264
Abstract
Normal levels of adenylate kinase (AK-1) and of α1-acid glycoprotein (ORM1) were found in a girl with a deletion 9q32-qter secondary to a maternal translocation (4q35; 9q32), thus excluding these loci from the deleted region. These results, and comparison with other informative data, map the locus for AK-1 to 9q32 and that for ORM1 to region 9q31-q32. The girl has several signs of the Goltz syndrome (focal dermal hypoplasia), which is listed in the McKusick catalog (no. 30560) as an X-linked dominant condition. Our finding indicates that the locus for Golz syndrome is autosomal and in region 9q32-qter or that there are two such conditions, one autosomal and one X-linked.This publication has 16 references indexed in Scilit:
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