G‐proteins in the signal‐transduction pathways of Dictyostelium discoideum
- 1 January 1988
- journal article
- molecular biology-of-signalling
- Published by Wiley in Developmental Genetics
- Vol. 9 (4-5) , 215-226
- https://doi.org/10.1002/dvg.1020090404
Abstract
The functional interaction of surface cAMP receptors with effector enzymes via G‐proteins was investigated in Dictyostelium discoideum. Several experimental conditions were used to investigate signal transduction, such as reduced temperatures, use of down‐regulated cells and of mutants. The results are presented as a model describing the complex interaction between multiple forms of the surface cAMP receptor and different G‐proteins that are responsible for the generation of the second messengers, cAMP, cGMP, InsP3 and Ca2+.Keywords
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