USE OF EDTA BLOOD SAMPLES FOR MANNOSIDOSIS TESTING

Abstract
Preincubation of EDTA plasma with 4mM ZnCl2 restores acidic alpha mannosidase activity, previously inhibited as a result of chelation of Zn++ by EDTA. This allows estimation of acidic alpha mannosidase activity in EDTA plasma samples, followed by granulocyte tests on those samples with low activities.

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