INHIBITION OF LYMPHOCYTE-TRANSFORMATION BY DISRUPTED MURINE ONCORNAVIRUS
- 1 January 1977
- journal article
- research article
- Vol. 37 (12) , 4529-4531
Abstract
Freeze-thaw preparations of banded Rauscher murine leukemia virus markedly suppressed the in vitro cellular-mediated blastogenic response of murine splenic lymphocytes to phytohemagglutinin-P and to allogeneic cells in 2-way mixed-leukocyte reaction. Suppression was not due to cytotoxicity or to virus-mitogen binding. A virion envelope component may interfere with cellular-mediated immunity by altering cell recognition sites.This publication has 4 references indexed in Scilit:
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