A controlled study of the influence of segregation of tuberculous patients for one year on the attack rate of tuberculosis in a 5-year period in close family contacts in South India.
- 1 January 1966
- journal article
- Vol. 34 (4) , 517-32
Abstract
This report is the last of a series of nine publications from the Tuberculosis Chemotherapy Centre, Madras, concerning various aspects of an investigation of the role of ambulatory chemotherapy for pulmonary tuberculosis. It presents the attack rates of tuberculosis over a 5-year period of follow-up of close family contacts of patients, all of whom were treated for one year with isoniazid plus PAS, half (selected at random) in sanatorium and half at home. The incidence of active tuberculosis and of tuberculous infections was no greater in the contacts of patients treated at home than in the contacts of patients treated in sanatorium, either in the first year or over the subsequent four years. The major risk to the contacts resulted from exposure to the patient before diagnosis. These findings reaffirm that close family contacts of patients treated at home were at no additional risk of developing tuberculosis, provided the patients received effective chemotherapy. Finally, this study has shown that it is possible in South India to obtain extremely good co-operation from a group of families over a period of several years.This publication has 13 references indexed in Scilit:
- Enhancing of tuberculin allergy by previous tuberculin testing.1966
- UNITED STATES PUBLIC HEALTH SERVICE TRIALS OF ISONIAZID PROPHYLAXIS.1964
- OBSERVATIONS ON THE PROTECTIVE EFFECT OF BCG VACCINATION IN A SOUTH INDIAN RURAL POPULATION.1964
- TUBERCULOSIS MORBIDITY IN A CONTROLLED TRIAL OF PROPHYLACTIC USE OF ISONIAZID AMONG HOUSEHOLD CONTACTSPublished by Elsevier ,1962
- Progress in the second and third years of patients with quiescent pulmonary tuberculosis after a year of chemotherapy at home or in sanatorium, and influence of further chemotherapy on the relapse rate.1961
- Influence of segregation to tuberculous patients for one year on the attack rate of tuberculosis in a 2-year period in close family contacts in South India.1961
- The role of diet in the treatment of pulmonary tuberculosis. An evaluation in a controlled chemotherapy study in home and sanatorium patients in South India.1961
- Progress in the second year of patients with quiescent pulmonary tuberculosis after a year of chemotherapy at home or in sanatorium, and influence of further chemotherapy on the relapse rate.1960
- Prevalence of tuberculosis among close family contacts of tuberculous patients in South India, and influence of segregation of the patient on early attack rate.1960
- Diluents for stabilization of tuberculin.1958