Quantitative polyphosphate-induced “prebiotic” peptide formation in H2O by addition of certain azoles and ions
- 1 February 1985
- journal article
- research article
- Published by Springer Nature in Journal of Molecular Evolution
- Vol. 21 (2) , 199-201
- https://doi.org/10.1007/bf02100094
Abstract
Aqueous solutions of 0.1 M amino acid and 0.1 M trimetaphosphate maintained at chosen pH values between 8.0 and 10.5 and at room temperature in the presence of imidazole or 1,2,4-triazole give rise after a few days to the corresponding peptides. Yields are highest when the pH is adjusted with concentrated NaOH or KOH instead of ammonia; in some cases glycine is quantitatively transformed within 10–15 days into peptides, mainly diand tripeptides.Keywords
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