Modification of NaCl appetite in the adrenalectomized rat consequent to extensive LiCl poisoning.

1 January 1970

journal article
Published by American Psychological Association (APA) in Journal of Comparative and Physiological Psychology

Vol. 72 (1) , 79-84
https://doi.org/10.1037/h0029314

Abstract

Exposed 6 groups of male Dublin/DR albino rats to 1 of 2 molarities of LiCl (.15 or .35) for 8 days along with water or .15 M NaCl. 16% of Ss died. The toxin was then removed and the Ss were given time to reestablish their pretoxic base weights. 1/2 of the groups were then adrenalectomized (ADX) and 1/2 were sham adrenalectomized (S-ADX). Not only did the S-ADX Ss drink more salt postoperatively but 2 of the ADX groups showed protracted weight losses and 4 Ss died. Results reinforce earlier findings on NaCl aversion subsequent to LiCl poisoning, but suggest that if such an aversion is intense enough it will interfere with compensatory salt hunger in the ADX rat. (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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