Canine Lymphoma: Relative Risk in the Boxer Breed

Abstract
Two hundred forty cases of canine lymphoma, from three regions, Midwest, South, end West Coast, and appropriate dog licensure control populations were analyzed, with relative risk techniques, to test the hypothesis that the boxer breed is at excess risk of developing canine lymphoma. Relative riskwas, in every instance, significantly higher (P<O.0005) for boxers than for other purebreds combined. No other single common breed demonstrated a similar pattern of increased risk. The summary relative risk of boxers for canine lymphoma, compared to all other purebreds, was approximately 6. There was no significant difference in sex distribution of dogs with lymphoma and controls. The question is raised as to whether the excess risk of boxers for canine lymphoma reflects an excess risk of boxers for all cancer. Possible implications to cancer research of this excess boxer risk are also discussed.

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