Reduction of Nitro Compounds with Borohydride Exchange Resin - Nickel Acetate
- 1 January 1993
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1993 (02) , 135-136
- https://doi.org/10.1055/s-1993-22377
Abstract
Borohydride Exchange Resin (BER) - nickel acetate system readily reduces both aliphatic and aromatic nitro compounds to the corresponding amino compounds in excellent yields in methanol. This system tolerates hydroxymethyl, phenol, methoxy, acetal, acetyl, carboxylic acid, ester, cyano and halogen (Cl and Br) substituents on the benzene ring.Keywords
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