CUTANEOUS HISTOPLASMOSIS

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Abstract
Cutaneous lesions as a manifestation of histoplasmosis, primarily a disease of the respiratory system, are rare and most commonly appear secondary to progressive dissemination. A patient with documented progressive disseminated histoplasmosis, previously treated with amphotericin B, presented on a 2nd occasion with cutaneous lesions as the chief complaint. Biopsy and cultures of these lesions were positive for Histoplasma capsulatum. A review of the English literature revealed only 7 reported cases of secondary skin histoplasmosis in 20 yr. All patients, including the current one, had diseases associated with depressed immunity or were receiving steroid therapy.

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