Carcinoma of the gallbladder–a natural history type of study

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Abstract
A retrospective analysis of the natural history of 63 consecutive patients with gallbladder cancer during 30 years at a county hospital in Sweden is presented. Dominating symptoms were pain, jaundice, weight loss, and a palpable mass. Fifty patients were subjected to surgery. Forty‐one patients had an extensive tumor spread in the abdominal cavity. Twenty‐six patients were cholecystectomized and in 24 patients biopsy from the tumor was the only measure taken. The gallbladder cancer was occult in four patients. The median survival time was 1 month in patients who underwent autopsy, 2 months in patients who were biopsied and 4 months in patients who were cholecystectomized. The overall 6‐month and 1‐year crude survival rates were 16% and 8%, respectively. Comparison with previous reports regardless of treatment reveals that the prognosis of gallbladder cancer is still dismal and unchanged.

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