Evaluation of Airway Interruption Technique as a Method for Measuring Pulmonary Air-Flow Resistance

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Abstract
Measurement of pulmonary resistance to air and tissue flow in 6 normal human subjects was made by comparing rates of air flow at the mouth with simultaneous non-elastic pressure differences occurring between the mouth and a point near the surface of the lungs (esophageal balloon). Values were nearly the same as those obtained in the same subjects by the method of V. Neergaard and Wirz in which rates of air flow measured at the mouth are compared with mouth pressures recorded following transient interruptions of the airstream by means of a solenoid valve in the mouth-piece assembly. Theoretical considerations supported the conclusion that the 2 methods give approximations of total pulmonary frictional resistance (air flow and tissue flow), and that the method of air-way interruption does not permit separate measurement of pulmonary air-flow resistance.

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