Approaches to the Total Synthesis of Calycotomine, a Widespread 1-Hydroxymethyl-Substituted Simple Tetrahydroisoquinoline
- 18 January 2005
- journal article
- review article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 2005 (03) , 339-360
- https://doi.org/10.1055/s-2005-861793
Abstract
1-Hydroxymethyl-substituted tetrahydroisoquinolines are scarce in nature; the widespread alkaloid calycotomine is its most prominent example. The different total syntheses of this natural product, used as test ground for the development of novel synthetic methodologies during the last forty years, and those of some structurally related precursors, are reviewed.Keywords
This publication has 0 references indexed in Scilit: