Blood Concentration of P-chloro-xylenol in Man Following Parenteral, Percutaneous and Rectal Application.

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Abstract
The presence of free p-chloroxylenol in the blood shows that this substance is resorbed after parenteral, oral, rectal, as well as percutaneous application. Only 1% of the amt. applied was detected in the blood. In percut. treatment, the skin acts as a depot from which the drug is slowly resorbed into the blood, and as a result a prolonged circulation is obtained. The prolonged circulation following different routes of admn. renders its chemotherapeutic efficacy in man comprehensible.

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