REBUCK SKIN WINDOW AS A GUIDE IN CANCER CHEMOTHERAPY

  • 1 January 1976
    • journal article
    • research article
    • Vol. 60  (7) , 903-906
Abstract
The skin window inflammatory cell response was studied in 64 adult patients with various malignant neoplasms before initiation of chemotherapy and was repeated when a neutrophil level of 2500 cells/mm3 or less occurred. Of the 21 neutropenic patients, 15 had an abnormal neutrophil cell response and 9 had an abnormal mononuclear cell response. Of the 9 patients who had infection, 8 had an abnormal mononuclear cell response and 7 of the 8 had a concomitant abnormal neutrophil response. The Rebuck skin window may be a practical clinical test to evaluate the risk for infection in neutropenic patients receiving cancer chemotherapy.

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