Alcaloïdes duPausinystalia macroceras

Abstract
A study of the alkaloidal content of trunk-barks of Pausinystalia macroceras (K. SCHUM.) PIERRE, Rubiaceae, resulted in the isolation of six alkaloids, five of which are indole alkaloids that belong to the yohimbane and heteroyohimbane groups; among them, yohimbine was found in major amount. Moreover, the levorotatory isomer of calycanthine, a quinoline dimeric tryptophane derived base, has been isolated for the first time. The phytochemical significance of calycanthine and related alkaloids is discussed.

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