Enantioselective synthesis of β-substituted butyric acid derivatives via orthoester Claisen rearrangement of enzymatically resolved allylic alcohols: application to the synthesis of (R)-(−)-baclofen
- 1 November 1997
- journal article
- Published by Elsevier in Tetrahedron: Asymmetry
- Vol. 8 (22) , 3801-3805
- https://doi.org/10.1016/s0957-4166(97)00538-7
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- A chemoenzymatic strategy for the synthesis of enantiopure (R)-(−)-baclofenTetrahedron Letters, 1997
- Microbially-aided preparation of (S)-2-Methoxycyclohexanone key intermediate in the synthesis of SanfetrinemTetrahedron, 1997
- Optical resolution of baclofen via diastereomeric salt pair formation between 3-(p-chlorophenyl)glutaramic acid and (S)-(−)-α-phenylethylamineJournal of the Chemical Society, Perkin Transactions 2, 1997
- Bakers' yeast-mediated synthesis of (R)-aminoglutethimide.The Journal of Organic Chemistry, 1995
- Bakers' Yeast Mediated Preparation of Esters of (R)- and (S)-Ethyl 2-Formyl-3-hydroxy-2-methylpropionateThe Journal of Organic Chemistry, 1994
- The thermal, aliphatic Claisen rearrangementChemical Reviews, 1988
- Quantitative analyses of biochemical kinetic resolutions of enantiomersJournal of the American Chemical Society, 1982
- The biological activity of d-baclofen (Lipresal®)European Journal of Pharmacology, 1978
- Baclofen in the Treatment of SpasticityBMJ, 1971
- Simple stereoselective version of the Claisen rearrangement leading to trans-trisubstituted olefinic bonds. Synthesis of squaleneJournal of the American Chemical Society, 1970