Culture of Brown-Pearce Carcinoma in the Embryonated Egg
- 1 August 1950
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 74 (4) , 784-789
- https://doi.org/10.3181/00379727-74-18049
Abstract
1. The Brown-Pearce carcinoma of rabbits shows definite growth on the chorioallantois in 58% of embryos implanted on the 8th day of incubation, and in 68% of embryos surviving until the 17th day. The wet weight of the tumor increases 79 fold during the 9-day culture period. 2. The average percentage of successful grafts is increased by implantation two or more pieces of tumor within a single egg, and by incubating the excised tumor for several hours in rabbit serum before implantation onto the chorioallantois. 3. The tumor does not metastasize from the chorioallantois in spite of apparent direct contact between the embryonic blood and the tumor cells.Keywords
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