A novel approach to site-specifically platinated oligonucleotides applying combinations of nucleobase protecting groups

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Abstract
Platination of a properly protected oligonucleotide followed by deprotection represents a new method for the synthesis of site-specific platinum-modified nucleic acids; N7 platination of 2′-deoxyguanosine can be circumvented by introducing a bulky protective group at the O6 position.

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