Loss of Cell-Associated Marek's Disease Vaccine Titer during Thawing, Reconstitution, and Use

Abstract
Tests of the effects of mismanagement practices observed in [chick] hatcheries showed that very subtle deviations from explicit directions accompanying Marek''s vaccine can cause dramatic losses of vaccine potency. Such mismanagement resulted in 14-97% loss of vaccine titer. Apparently procedures used in hatcheries for the handling of cell-associated Marek''s vaccine should be closely monitored on a continuous basis to prevent a gradual drift from correct handling.