Synthesis and preliminary in vivo evaluation of 4-[123I]iodo-N-{2-[4-(6-trifluoromethyl-2-pyridinyl)-1-piperazinyl]ethyl}benzamide, a potential SPECT radioligand for the 5-HT1A receptor
- 1 January 2001
- journal article
- research article
- Published by Wiley in Journal of Labelled Compounds and Radiopharmaceuticals
- Vol. 44 (1) , 73-88
- https://doi.org/10.1002/jlcr.434
Abstract
No abstract availableKeywords
This publication has 8 references indexed in Scilit:
- Animal models for studying serotonin (5-ht) receptor subtypes: relationship to 5-ht system pathologiesNuclear Medicine and Biology, 1998
- Derivatives of way 100635 as potential imaging agents for 5-ht1a receptors: syntheses, radiosyntheses, and in vitro and in vivo evaluationNuclear Medicine and Biology, 1998
- Exquisite delineation of 5-HT1A receptors in human brain with PET and [carbonyl-11C]WAY-100635European Journal of Pharmacology, 1996
- Serotonin receptors: Subtypes, functional responses and therapeutic relevancePharmacology & Therapeutics, 1995
- 5-HT1A receptor agonists: recent developments and controversial issuesPsychopharmacology, 1995
- Selective in vivo labelling of brain 5-HT1A receptors by [3H]WAY 100635 in the mouseEuropean Journal of Pharmacology, 1994
- In vivo binding of [123I]4‐(2′‐methoxy phenyl)‐1‐[2′‐(N‐2″‐pyridinyl)‐P‐iodobenzamido‐]ethyl‐piperazine, p‐MPPI, to 5‐HT1A receptors in rat brainSynapse, 1994
- Synthesis And Evaluation of 4-(2'-Methoxyphenyl)-1-[2'-[N-(2''-pyridinyl)- p-iodobenzamido]ethyl]piperazine (p-MPPI): A New Iodinated 5-HT1A LigandJournal of Medicinal Chemistry, 1994