Partial Cystectomy Followed by Postoperative Irradiation in Treatment of Bladder Carcinoma (P(2)/P(3))

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Abstract
The 5 and 10 yr survival rate was 25 and 16%, respectively, in 107 patients with [stage] P2 and P3 bladder carcinoma treated with partial cystectomy followed by postoperative high voltage irradiation. The depth of tumor infiltration was of major prognostic significance through patients with P3a tumors had a significantly better prognosis than those with P2 carcinomas. Within the same P category, the histological differentiation represented no prognostic factor. Patients with tumors without blood vessel and/or lymphatic vessel infiltration survived significantly longer than patients with such infiltration. High voltage postoperative irradiation prolonged survival in some patient groups (non-radically operated tumors, early tumor recurrence, grade III tumors) only if irradiation was supplied with high cumulative radiation effect (CRE) values.