Argyrosis and Cyanosis—Melanosis and Cyanosis

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Abstract
Silver enters the body in various chemical combinations, the most popular in the past being silver nitrate pills ingested over a period of years for gastrointestinal ailments. This form of therapy is no longer in use. Silver, however, still enters the body in the form of nasal drops or eye drops or as a result of handling the metal (silversmiths). Silver is not excreted like most drugs but remains in the body, deposited permanently in the skin, producing a gray-discolored skin. The shade of gray may be very light or very deep according to the area of the body and the amount of silver stored in the cutaneous surface. Parts exposed to sunlight are deep gray. When the shade of gray is very deep, the diagnosis of argyrosis is obvious. Difficulty arises when the amount of silver taken in was small and the shade of gray is light. Difficulty

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