Deficiency of IgG Subclasses in Mothers of Infants with Group B Streptococcal Septicemia
- 1 January 1983
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 72 (3) , 249-252
- https://doi.org/10.1159/000234876
Abstract
Serum IgG subclasses were studied in 19 mothers of infants with serious infections caused by group B streptococci (GBS) and compared with a control group of 20 mothers of healthy infants. 13 of 19 mothers showed decreased subclass levels: 10 of 19 low IgG2, 9 of 19 low IgG1 and 4 of 19 low IgG3. The levels of IgG1, IgG2 and IgG3 were significantly lower among mothers of GBS-infected infants than among the controls. Thus, there is indirect evidence that the infants were immunodeficient at birth.Keywords
This publication has 2 references indexed in Scilit:
- Correlation between Serum IgG-2 Concentrations and the Antibody Response to Bacterial Polysaccharide AntigensNew England Journal of Medicine, 1980
- Quantitation of Serum Antibodies to Surface Antigens of Group B Streptococci Types Ia, Ib, and III: Low Antibody Levels in Mothers of Neonatally Infected InfantsScandinavian Journal of Infectious Diseases, 1980