Automated Talairach Atlas labels for functional brain mapping
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- 1 July 2000
- journal article
- research article
- Published by Wiley in Human Brain Mapping
- Vol. 10 (3) , 120-131
- https://doi.org/10.1002/1097-0193(200007)10:3<120::aid-hbm30>3.0.co;2-8
Abstract
An automated coordinate-based system to retrieve brain labels from the 1988 Talairach Atlas, called the Talairach Daemon (TD), was previously introduced [Lancaster et al., 1997]. In the present study, the TD system and its 3-D database of labels for the 1988 Talairach atlas were tested for labeling of functional activation foci. TD system labels were compared with author-designated labels of activation coordinates from over 250 published functional brain-mapping studies and with manual atlas-derived labels from an expert group using a subset of these activation coordinates. Automated labeling by the TD system compared well with authors' labels, with a 70% or greater label match averaged over all locations. Author-label matching improved to greater than 90% within a search range of ±5 mm for most sites. An adaptive grey matter (GM) range-search utility was evaluated using individual activations from the M1 mouth region (30 subjects, 52 sites). It provided an 87% label match to Brodmann area labels (BA 4 & BA 6) within a search range of ±5 mm. Using the adaptive GM range search, the TD system's overall match with authors' labels (90%) was better than that of the expert group (80%). When used in concert with authors' deeper knowledge of an experiment, the TD system provides consistent and comprehensive labels for brain activation foci. Additional suggested applications of the TD system include interactive labeling, anatomical grouping of activation foci, lesion-deficit analysis, and neuroanatomy education. Hum. Brain Mapping 10:120–131, 2000.Keywords
This publication has 35 references indexed in Scilit:
- Accurate High-Speed Spatial Normalization Using an Octree MethodNeuroImage, 1999
- A PET study of the neural systems of stutteringNature, 1996
- Quantitative Comparisons of Image Registration Techniques Based on High-Resolution MRI of the BrainJournal of Computer Assisted Tomography, 1994
- MRI-PET Registration with Automated AlgorithmJournal of Computer Assisted Tomography, 1993
- Comparing Functional (PET) Images: The Assessment of Significant ChangeJournal of Cerebral Blood Flow & Metabolism, 1991
- Specification and Selection of Regions of Interest (ROIs) in a Computerized Brain AtlasJournal of Cerebral Blood Flow & Metabolism, 1991
- MRI-PET Correlation in Three Dimensions Using a Volume-of-Interest (VOI) AtlasJournal of Cerebral Blood Flow & Metabolism, 1991
- Localisation in PET Images: Direct Fitting of the Intercommissural (AC—PC) LineJournal of Cerebral Blood Flow & Metabolism, 1989
- Cerebral Cortical LocalizationJournal of Computer Assisted Tomography, 1989
- Enhanced Detection of Focal Brain Responses Using Intersubject Averaging and Change-Distribution Analysis of Subtracted PET ImagesJournal of Cerebral Blood Flow & Metabolism, 1988