Reactions of the α‐tocopheroxyl radical in micellar solutions studied by nanosecond laser flash photolysis
- 23 September 1991
- journal article
- Published by Wiley in FEBS Letters
- Vol. 290 (1-2) , 205-208
- https://doi.org/10.1016/0014-5793(91)81260-f
Abstract
Laser flash photolysis of α-tocopherol in methanol and in aqueous micellar solutions has been shown to produce the α-tocopheroxyl radical. The reaction between the α-tocopheroxyl radical and ascorbate in positively charged hexadecyltrimethylammonium chloride (HTAC) micelles occurred with a second order rate constant of 7.2 × 107 M−1·s−1, whereas in negatively charged sodium dodecyl sulphate (SDS) micelles the rats constant was only 3.8 × 104 M−1·s−1. The α-tocopheroxyl radical was found to be relatively long-lived in HTAC micelles (t½ ⩾ 5 min), allowing the slow disappearance of the α-tocopheroxyl radical by reaction with glutathione to be observed.Keywords
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