Prediction of protein folding rates from the amino acid sequence-predicted secondary structure
- 7 June 2004
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 101 (24) , 8942-8944
- https://doi.org/10.1073/pnas.0402659101
Abstract
We present a method for predicting folding rates of proteins from their amino acid sequences only, or rather, from their chain lengths and their helicity predicted from their sequences. The method achieves 82% correlation with experiment over all 64 "two-state" and "multistate" proteins (including two artificial peptides) studied up to now.Keywords
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