Production of hemagglutinins and pili by Vibrio mimicus and its adherence to human and rabbit small intestines in vitro
- 1 February 1992
- journal article
- research article
- Published by Oxford University Press (OUP) in FEMS Microbiology Letters
- Vol. 91 (1) , 73-78
- https://doi.org/10.1016/0378-1097(92)90565-6
Abstract
Clinical isolate of Vibrio mimicus were examined for production of cell-associated hemagglutinin (HA) and pili and for adherence to formalin-fixed human intestinal mucosa, V. mimicus grown on CFA agar for 3 h at 37°C possessed HA and adhered better to the mucus layer than to the epithelial cell surface. A significant correlation was found between the HA titers and adherence ability to the epithelial cell surface of villi (P < 0.05); adherence to the ileal lymphoid follicle associated epithelium occured at higher levels. In contrast, V. mimicus grown on CFA agar for 20 h at 37°C exhibited lower levels of HA and reduced adherence ability. The production of pili was more pronounced after 20 h of incubation than after 3 h of incubation. In comparison with V. cholerae 01 and V. cholerae non-01 cultured under similar conditions, V. mimicus showed inferior adherence, but with similar HA production or piliation.Keywords
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