Design and synthesis of monocyclic β-lactams as mechanism-based inhibitors of human cytomegalovirus protease
- 1 February 1998
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 8 (4) , 365-370
- https://doi.org/10.1016/s0960-894x(98)00032-8
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- Herpesvirus proteases: targets for novel antiviral drugsAntiviral Research, 1997
- Structure of the Human Cytomegalovirus Protease Catalytic Domain Reveals a Novel Serine Protease Fold and Catalytic TriadCell, 1996
- Unique fold and active site in cytomegalovirus proteaseNature, 1996
- A new serine-protease fold revealed by the crystal structure of human cytomegalovirus proteaseNature, 1996
- Three-dimensional structure of human cytomegalovirus proteaseNature, 1996
- Azetidin-2-one derivatives as inhibitors of thrombinBioorganic & Medicinal Chemistry, 1995
- Assemblin, a herpes virus serine maturational proteinase and new molecular target for antiviralsPerspectives in Drug Discovery and Design, 1995
- Orally active .beta.-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinonesJournal of Medicinal Chemistry, 1992
- Enantioselective synthesis of 3-amino-2-azetidinones via the ester enolate - imine condensationThe Journal of Organic Chemistry, 1992
- Monocyclic β-lactam inhibitors of human leukocyte elastaseTetrahedron, 1990