Endometrial Cancer as an Estrogen-Progesterone Target
- 23 March 1972
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 286 (12) , 645-647
- https://doi.org/10.1056/nejm197203232861207
Abstract
ESTROGEN and progesterone have long stood as the sole controlling agents in the growth of the endometrium, and both agents have long been available for therapeutic purposes in the form of chemically modified preparations of high potency. It has proved possible and profitable to reproduce the sequence of morphologic changes that are normal for the menstrual cycle, to produce pregnancy-like changes that are symptomatically beneficial in the treatment of endometriosis, and to produce abnormal alterations, in which stroma and glands are not in phase with each other, to prevent the implantation of a fertilized ovum.Another and even greater triumph . . .Keywords
This publication has 2 references indexed in Scilit:
- Mechanisms of Action of Steroid HormonesNew England Journal of Medicine, 1971
- Growth-Hormone Secretion in Patients with Endometrial CarcinomaNew England Journal of Medicine, 1969