Microbial transformation of daunomycinone by Streptomyces aureofaciens B-96.
- 1 January 1976
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 29 (11) , 1199-1202
- https://doi.org/10.7164/antibiotics.29.1199
Abstract
Daunomycinone, aglycone of the anthracycline antibiotic daunomycin, was transformed by a washed mycelia of S. aureofaciens B-96 in a buffer solution containing sucrose; the obtained product, dihydrodaunomycinone(9-(1-hydroxyethyl)-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-4-methoxy-5,12-naphthacenequinone), was identified by measuring basic physico-chemical characteristics (IR, UV and visible spectra, mass spectra and NMR, optical rotation and m.p. [melting point]).This publication has 0 references indexed in Scilit: