Steroid sulphatase activity in trophoblast samples
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in Journal of Obstetrics and Gynaecology
- Vol. 5 (1) , 24-26
- https://doi.org/10.3109/01443618409075738
Abstract
Summary Trophoblast samples were collected transcervically from 16 pregnant women who were undergoing termination of pregnancy at 8 to 13 weeks. Steroid sulphatase and arylsulphatase C activities were assayed on cultured and uncultured chorionic villi, whole fetal membrane homogenate and cultured cells from fetal membrane. High enzyme activities were detected in uncultured chorionic villi, suggesting that it is possible to make the antenatal diagnosis of X-linked ichthyosis by trophoblast sampling.Keywords
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