Structure of bovine trypsinogen at 1.9 Å resolution
- 22 February 1977
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 16 (4) , 654-664
- https://doi.org/10.1021/bi00623a016
Abstract
The 3-dimensional crystal structure of bovine trypsinogen at .apprx. pH 7.5 was initially solved at 2.6 .ANG. resolution using the multiple isomorphous replacement method. Preliminary refinement cycles of the atomic coordinates for trypsinogen were carried out first to a resolution of 2.1 .ANG., and later to 1.9 .ANG., using constrained difference Fourier refinement. During the process, structure factors Fc and .phi.c were calculated from the trypsinogen structure and final interpretation was based on an electron-density map computed with terms (2This publication has 5 references indexed in Scilit:
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