A New Therapeutic Antibody Removal Method Using Antigen‐Positive Red Cells

Abstract
Therapeutic antibody removal using antigen-positive red cells was applied to a pregnant woman who has high titered IgG anti-P and had lost all of 4 previous fetuses in P-incompatible pregnancy. The treatment was commenced at the 6th wk of gestation and was intensively performed 93 times up to the 35th wk. The volume of plasma treated was 2.31/procedure on the average and totaled 215 l. The antibody titer was kept at a low level. At the end of the 35th wk of gestation a female infant was delivered by cesarean section. The baby did not require an exchange transfusion and encountered no complications.