THE EFFECT OF VARIOUS ACTH EXTRACTS ON THE GONADS
- 1 June 1954
- journal article
- research article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 10 (4) , 291-301
- https://doi.org/10.1677/joe.0.0100291
Abstract
SUMMARY: ACTH extracts showing inhibition of the stimulatory action of PMS on follicular maturation in infantile female rats and slight stimulation of the growth of the testes and accessory sex organs in infantile male rats and day-old chicks have been investigated. The action of these extracts on the gonads was found to be independent of the adrenal ascorbic acid depleting principle, as ACTH fractions free from inhibitory or stimulatory influence on the gonads could be prepared. The nature of the factor described is discussed.Keywords
This publication has 2 references indexed in Scilit:
- EXTRACTION AND PURIFICATION OF CORTICOTROPINJournal of Biological Chemistry, 1950
- Some Studies of the Chemistry and Pharmacology of Adrenocorticotrophic HormoneJournal of Pharmacy and Pharmacology, 1950