Studies of carbachol-induced wet-dog shake behavior in rats
- 1 January 1981
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 73 (1) , 81-83
- https://doi.org/10.1007/bf00431107
Abstract
Intraventricular administration of carbachol chloride evoked wet-dog shakes (WDS) in rats in a dose-related manner. WDS induced by carbachol at the dose of 20 μg were antagonized by scopolamine, atropine, cyproheptadine, morphine, clonidine, phentolamine, haloperidol, and l-5-hydroxytryptophan (5-HTP). Methergoline, propranolol, bicuculline, and aminooxyacetic acid had no effect on carbachol-induced shaking behavior. The present experiments show the existence of different types of shaking behavior, not exclusively related to the stimulation of central 5-HT structures.Keywords
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