PROLONGED AND ACCURATELY TIMED INTRAVENOUS INJECTIONS OF SUGAR

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Abstract
The study of sugar tolerance and the effects of prolonged uniform injections of glucose by vein, of which this is an abbreviated report, was undertaken primarily for the purpose of perfecting an accurate clinical method for estimating the sugar-using powers of different individuals. It was also anticipated that the data which would be obtained could not fail to have other applications, and that the method employed might be in itself of general interest as a means of studying problems of absorption, metabolism and elimination, and have therapeutic application. Expectations concerning all of these things have been fulfilled. The study was based on certain prior ideas which were in part original and in part conceptions which had been expressed before by Doyon and DuFort in 1901, and by Blumenthal in 1906. These may be stated briefly: 1. It is at present a common clinical practice to estimate sugar tolerance as the

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