Abstract
The literature is reviewed and the general relations summarized in schematic form. The crucial factor determining the direction of this over-all biological equilibrium is a supply of exogenous energy, or the lack of it.[image].The net change from left to right, thermodynamically, is exergonic, with a net reduction in cell material. From right to left, the change is endergonic, with a net material gain in cell substance. While a precise formulation for the mechanism of metamorphosis of a vegetative cell into a spore cell cannot be given at present, the author is optimistic about its final elucidation.
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