Adrenal Medullary Enkephalin-Like Peptides May Mediate Opioid Stress Analgesia
- 6 August 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 217 (4559) , 557-559
- https://doi.org/10.1126/science.7089582
Abstract
Different patterns of fact shock activate opioid and nonopioid mechanisms of stress analgesia in the rat. Opioid, but not nonopioid, stress analgesia is reduced by adrenal demedullation and denervation and is potentiated by reserpine, a drug known to increase concentrations of adrenal medullary enkephalin-like peptides. It is suggested that adrenal enkephalins mediate opioid stress analgesia.This publication has 31 references indexed in Scilit:
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