Vitamin A Pretreatment of Stress Ulcers in Rats
- 1 March 1973
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Surgery
- Vol. 106 (3) , 320-321
- https://doi.org/10.1001/archsurg.1973.01350150054015
Abstract
Fifty male rats, divided into two groups, were tested for the effect of pretreatment with vitamin A on the occurrence of stress ulcers. The experimental rats received a total of 10,000 international units of vitamin A prior to an eight-hour period of restraint in a modified flexible wire gauze restraining device. No differences were found between the experimental and control groups in the frequency of ulcerated stomachs or the mean numbers of ulcers per stomach. It is concluded that vitamin A exerts a negligible, if any, protective effect on the occurrence of gastric ulceration in the rat produced by the stress of restraint.This publication has 3 references indexed in Scilit:
- Prevention of stress ulcersThe American Journal of Surgery, 1971
- Metabolism of Sulfated Mucopolysaccharides in Vitamin A DeficiencyThe American Journal of Clinical Nutrition, 1969
- Studies on the function of vitamin A in mucopolysaccharide biosynthesisBiochimica et Biophysica Acta, 1960