On a prezygotic origin of normal/balanced translocation mosaics.

  • 1 January 1986
    • journal article
    • Vol. 29  (4) , 221-2
Abstract
Based on a theoretical model for the production of some structural mosaicisms, the authors propose a mechanism for the origin of normal/balanced translocation mosaics. Single strand breaks and nonhomologous hemichromatid joining are implicated and, when applied to homologous chromosomes, could explain some instances of nondisjunction independent of centromere function.

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