Synthesis of peptides from amino acids and ATP with lysine-rich proteinoid
- 1 June 1980
- journal article
- research article
- Published by Springer Nature in Journal of Molecular Evolution
- Vol. 15 (2) , 161-168
- https://doi.org/10.1007/bf01732668
Abstract
Lysine-rich proteinoids in aqueous solution catalyze the formation of peptides from free amino acids and ATP. This catalytic activity is not found in acidic proteinoids, even though the latter contain some basic amino acid. The pH optimum for the synthesis is about 11, but is appreciable below 8 and above 13. Temperature data indicate an optimum at 20°C or above, with little increase in rate to 60°C. Pyrophosphate can be used instead of ATP, with lesser yields resulting. The ATP-aided syntheses of peptides in aqueous solution occur with several types of proteinous amino acid.Keywords
This publication has 23 references indexed in Scilit:
- On the experimental silicification of microorganisms II. On the time of appearance of eukaryotic organisms in the fossil recordPrecambrian Research, 1978
- Thermal Polyamino Acids: Synthesis at Less Than 100°CScience, 1976
- Coacervate-like microspheres from lysine-rich proteinoidDiscover Life, 1975
- A re-examination of the zeolite-promoted, clay-mediated peptide synthesisJournal of Molecular Evolution, 1974
- Studies in prebiotic synthesisJournal of Molecular Biology, 1972
- The therml synthesis of neutral and basic proteinoidsBiochimica et Biophysica Acta (BBA) - Protein Structure, 1968
- Bildung von Aminosäuren und Aminosäurevorstufen aus primitiven Verbindungen bei der HochtemperatursyntheseAngewandte Chemie, 1967
- Synthesis of Pyrophosphate Under Primitive Earth ConditionsNature, 1964
- Thermal Synthesis of Natural Amino-Acids from a Postulated Primitive Terrestrial AtmosphereNature, 1964
- Synthesis of adenine from ammonium cyanideBiochemical and Biophysical Research Communications, 1960