Effect of brain stem transections on blood pressure responses to medullary stimulation

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Abstract
Electrical stimulation in the posterior medulla of the unanesthetized rabbit shows diffuse distribution and intermingling of pressor and depressor points. Transverse transections, caudally of the hypothalamus, convert the majority of bulbar pressor responses into depressor reactions. This effect is similar to the barbiturate-induced reversal of hypertensive responses. It is assumed that medullary pressor neurons act mainly through higher brain centers, while the bulbar depressor elements have chiefly descending connections to the spinal cord, in addition to some ascending links.