The reactivity of the disulphide bonds of bovine pancreatic ribonuclease with glutathione
- 1 September 1965
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 96 (3) , 890-894
- https://doi.org/10.1042/bj0960890
Abstract
Bovine pancreatic ribonuclease is not reduced by GSH at near-physiological concentrations and pH. Disruption of the structure of ribonuclease by proteolytic enzymes leads to products that can be reduced by GSH. At higher temperatures the disulphide bonds of ribonuclease are completely reduced by GSH in a coupled system. The Ttr is 51 [degree] and this has been found to be lower than the Ttr for the abnormal tyrosine residues under the same conditions.This publication has 19 references indexed in Scilit:
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