A warning against the use of corticotrophin (ACTH) and cortisone not only in patients with active tuberculosis but also in patients with latent tuberculous infection was issued a few months ago by the Committee on Medical Research of the American Trudeau Society, in the Bulletin of the National Tuberculosis Association.1 In a subsequent issue of the Bulletin, Tucker2 again emphasized the danger of the use of ACTH and cortisone in the tuberculous patient. Spain and Molomut3 described the effect of cortisone in guinea pigs experimentally infected with tuberculosis. The lesions in those animals receiving cortisone appeared to be more extensive and less well localized than in control animals that did not receive cortisone. In an editorial in The Journal, March 24, 1951,4 the suggestion is issued that caution should be exercised in the administration of cortisone to patients with tuberculosis. This suggestion is made as a